Jorge Diaz

Melvin (voice) / Melvin / Melvinborg (voice)

39 eps

Dayci Brookshire

Jessica / Dressy (voice)

39 eps

Evan Kishiyama

Steve 'Gooch' Yamaguchi (voice)

39 eps

Erica Luttrell

Erica (voice) / Werica Ang (voice) / Erica / Plungerina (voice) / Grace Wain (voice)

8 eps

Laraine Newman

Ms. Ribble (voice) / Ms. Ribble / Dr. Mentor (voice) / Dr. Mentor / Ms. Ribble (voice) / Female Cop (voice) / Ms. Ribble / Queen Zombee (voice) / Ms. Ribble / Malison Saurus (voice)

8 eps

David Koechner

Mr. Meaner (voice) / Mr. Meaner / Flabby Flabulous (voice) / Dr. Will Boryew (voice) / Mr. Meaner / Sergeant Boxers (voice) / Mr. Meaner / Mr. Neamer / Brainy Blabulous (voice)

6 eps

Patty Mattson

Miss Anthrope (voice) / Miss Anthrope / Clogneta (voice) / Miss Anthrope / Chalice Aristocrab (voice)

6 eps

Clancy Brown

Mr. Ree (voice) / Mr. Ree / Splotch (voice)

4 eps

Eric Bauza

Rap Talkwell / Mr. Gigglenose (voice) / Rap Talkwell (voice) / Robius (voice)

3 eps

Kevin Michael Richardson

George's Dad / Dune Buggy (voice) / Diddlysaurus / The Schmoozer (voice) / Diddlysaurus / Fingers (voice)

3 eps